It's sort of a toss-up, because both are really strange:
In The Whispering Vault you play humans recruited to capture supernatural beings. Each session involved doing things like bullying your way through dimensional barriers and having a new body woven for you for your time on Earth. A body which, by the way, could shoot chains out of its eye sockets. Each session had a rather formulaic approach, but was chock-full of weird contemporary fantasy.
I also owned Over the Edge. or Naked Lunch the RPG. Build whatever you want and go live on a psychedelic island that vaguely resembles Madagascar. Looking to game Lost? Here you go.