First, I'd love to see a Lost Girl RPG.
As I mentioned above, I think it would be easy-peasy to go this campaign by hacking the Angel RPG, but I'd love for someone other than me to do it.
My second, because I always seem to have two answers to every question, is a Warehouse 13 RPG.
Investigators trying to locate historical objects imbued with almost supernatural abilities, all the while trying to stay under the radar of society? Again, a really easy sell.
This one I've actually done, or at least sketched out for my kids, using the FATE system. You've got Pete (Alcoholic Ex-Marine, Just Having Some Fun), Mika (Raised in a Bookstore, Haunted by Failure), Artie (Former Cold War Spy, Never Lose an Agent), Claudia (Impulsive Inventor, Destined to Become the Caretaker), and Steve (Gay Buddhist DEA Agent, Second Stringer).
So I really don't need this one, but the first would be fantastic.